Noninvasive Cardiac Radiation for Ablation of Ventricular Tachycardia.

ABSTRACT:

Background

Recent advances have enabled noninvasive mapping of cardiac arrhythmias with electrocardiographic imaging and noninvasive delivery of precise ablative radiation with stereotactic body radiation therapy (SBRT). We combined these techniques to perform catheter-free, electrophysiology-guided, noninvasive cardiac radioablation for ventricular tachycardia.

Methods

We targeted arrhythmogenic scar regions by combining anatomical imaging with noninvasive electrocardiographic imaging during ventricular tachycardia that was induced by means of an implantable cardioverter-defibrillator (ICD). SBRT simulation, planning, and treatments were performed with the use of standard techniques. Patients were treated with a single fraction of 25 Gy while awake. Efficacy was assessed by

SUBMITTER: Cuculich PS 

PROVIDER: S-EPMC5764179 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature