Platelet-rich plasma to treat experimentally-induced skin wounds in animals: A systematic review and meta-analysis.

ABSTRACT: The objective of the study was to review current literature to determine whether the topical application of platelet-rich plasma (PRP) promotes healing in experimentally-induced full-thickness skin wounds in animals. The hypothesis was that the adjunct of PRP has a positive effect on wound healing. An electronic search was carried out on the following databases: Web of Science, Cochrane Library, PubMed, Research Gate, Cochrane Wounds Group, Veterinary Information Network. No publication date nor language restrictions were applied. Randomised and not randomised controlled clinical trials comparing PRP with placebo or with other treatments were included. The reduction of open wound area in PRP-treated (test) wounds compared to control wounds was the primary outcome. Secondary outcomes were h

SUBMITTER: Tambella AM 

PROVIDER: S-EPMC5764374 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature