Clinical risk stratification model for advanced colorectal neoplasia in persons with negative fecal immunochemical test results.

ABSTRACT:

Objectives

The fecal immunochemical test (FIT) has low sensitivity for detecting advanced colorectal neoplasia (ACRN); thus, a considerable portion of FIT-negative persons may have ACRN. We aimed to develop a risk-scoring model for predicting ACRN in FIT-negative persons.

Materials and methods

We reviewed the records of participants aged ≥40 years who underwent a colonoscopy and FIT during a health check-up. We developed a risk-scoring model for predicting ACRN in FIT-negative persons.

Results

Of 11,873 FIT-negative participants, 255 (2.1%) had ACRN. On the basis of the multivariable logistic regression model, point scores were assigned as follows among FIT-negative persons: age (per year from 40 years old), 1 point; current smoker, 10 points; overweight, 5 points; ob

SUBMITTER: Jung YS 

PROVIDER: S-EPMC5764375 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature