Continental synchronicity of human influenza virus epidemics despite climatic variation.

ABSTRACT: The factors that determine the pattern and rate of spread of influenza virus at a continental-scale are uncertain. Although recent work suggests that influenza epidemics in the United States exhibit a strong geographical correlation, the spatiotemporal dynamics of influenza in Australia, a country and continent of approximately similar size and climate complexity but with a far smaller population, are not known. Using a unique combination of large-scale laboratory-confirmed influenza surveillance comprising >450,000 entries and genomic sequence data we determined the local-level spatial diffusion of this important human pathogen nationwide in Australia. We used laboratory-confirmed influenza data to characterize the spread of influenza virus across Australia during 2007-2016. The onset of

SUBMITTER: Geoghegan JL 

PROVIDER: S-EPMC5764404 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature