The J-curve between Diastolic Blood Pressure and Risk of All-cause and Cardiovascular Death.

ABSTRACT: BACKGROUND AND OBJECTIVES:The J-curve phenomenon between diastolic blood pressure (DBP) and mortality has been reported repeatedly in treated patients. However, the baseline risk of low DBP has not been fully explored. This study was to examine the relationship between DBP and risk of mortality from all-cause, atherosclerotic vascular diseases (ASCVD), and ischemic heart disease (IHD) using a prospective cohort of general population. METHODS:We analyzed 1,234,435 participants of the Korean Cancer Prevention Study cohort (789,255 men, 30-95 years of age) who had a medical evaluation from 1992 to 1995 using Cox proportional hazards models. RESULTS:A total of 22.5 million person-years were followed up (mean age 46.6 years, deaths 193,903 cases). The hazard ratios of mortality from all-cause a

SUBMITTER: Kimm H 

PROVIDER: S-EPMC5764869 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature