Evaluation of animal-to-human and human-to-human transmission of influenza A (H7N9) virus in China, 2013-15.

ABSTRACT: A novel avian-origin influenza A(H7N9) virus emerged in China in March 2013 and by 27 September 2017 a total of 1533 laboratory-confirmed cases have been reported. Occurrences of animal-to-human and human-to-human transmission have been previously identified, and the force of human-to-human transmission is an important component of risk assessment. In this study, we constructed an ecological model to evaluate the animal-to-human and human-to-human transmission of H7N9 during the first three epidemic waves in spring 2013, winter/spring 2013-2014 and winter/spring 2014-2015 in China based on 149 laboratory-confirmed urban cases. Our analysis of patterns in incidence in major cities allowed us to estimate a mean incubation period in humans of 2.6 days (95% credibility interval, CrI: 1.4-3.1)

SUBMITTER: Virlogeux V 

PROVIDER: S-EPMC5765021 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature