Partial Conduction Block as an Early Nerve Conduction Finding in Neurolymphomatosis.

ABSTRACT: BACKGROUND AND PURPOSE:Neurolymphomatosis is a rare manifestation of hematological malignancy and is characterized by direct infiltration of the peripheral nervous system. The objective of this study was to identify the clinical and electrophysiological features of neurolymphomatosis. METHODS:We retrospectively analyzed the medical records of 13 patients with neurolymphomatosis. Seven (54%) of the patients were men, and the median age at symptom onset was 60.0 years. RESULTS:The most common type of underlying malignancy was diffuse large B-cell lymphoma (69%). Twelve patients had painful asymmetric neuropathies. The median survival time after diagnosis was 7 months, and 12 patients died during the study period. Thirty-eight motor nerve conduction studies (NCSs) were performed in the affect

SUBMITTER: Park HJ 

PROVIDER: S-EPMC5765259 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature