Associations of coffee genetic risk scores with consumption of coffee, tea and other beverages in the UK Biobank.

ABSTRACT:

Aims

To evaluate the utility of coffee-related genetic variants as proxies for coffee consumption in Mendelian randomization studies, by examining their association with non-alcoholic beverage consumption (including subtypes of coffee and tea) and a range of socio-demographic and life-style factors.

Design

Observational study of the association of genetic risk scores for coffee consumption with different types of non-alcoholic beverage consumption.

Setting

UK general population.

Participants

Individuals of European ancestry aged 40-73 years from the UK Biobank between 2006 and 2010 (n = 114 316).

Measurements

Genetic risk scores were constructed using two, four and eight independent single nucleotide polymorphisms (SNPs) identified in genome-wide associa

SUBMITTER: Taylor AE 

PROVIDER: S-EPMC5765424 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature