Long-term effects of cognitive rehabilitation on brain, functional outcome and cognition in Parkinson's disease.

ABSTRACT:

Background and purpose

Cognitive rehabilitation has demonstrated efficacy in producing short-term cognitive and brain changes in patients with Parkinson's disease (PD). To date, no study has assessed the long-term effects of cognitive rehabilitation using neuroimaging techniques in PD. The aim was to assess the longitudinal effects of a 3-month cognitive rehabilitation programme evaluating the cognitive, behavioural and neuroimaging changes after 18 months.

Methods

Fifteen patients with PD underwent a cognitive, behavioural and neuroimaging assessment at pre-treatment (T₀ ), post-treatment (T₁ ) and after 18 months (T₂ ). This study examined the long-term effects (from T₀ to T₂ ) and the maintenance of the changes (from

SUBMITTER: Diez-Cirarda M 

PROVIDER: S-EPMC5765471 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature