Guidelines in CHARGE syndrome and the missing link: Cranial imaging.

ABSTRACT: "CHARGE syndrome" is a complex syndrome with high and extremely variable comorbidity. As a result, clinicians may struggle to provide accurate and comprehensive care, and this has led to the publication of several clinical surveillance guidelines and recommendations for CHARGE syndrome, based on both single case observations and cohort studies. Here we perform a structured literature review to examine all the existing advice. Our findings provide additional support for the validity of the recently published Trider checklist. We also identified a gap in literature when reviewing all guidelines and recommendations, and we propose a guideline for neuroradiological evaluation of patients with CHARGE syndrome. This is of importance, as patients with CHARGE are at risk for peri-anesthetic compli

SUBMITTER: de Geus CM 

PROVIDER: S-EPMC5765497 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature