Effect of HPV vaccination and cervical cancer screening in England by ethnicity: a modelling study.

ABSTRACT:

Background

Health equality is increasingly being considered alongside overall health gain when assessing public health interventions. However, the trade-off between the direct effects of vaccination and herd immunity could lead to unintuitive consequences for the distribution of disease burden within a population. We used a transmission dynamic model of human papillomavirus (HPV) to investigate the effect of ethnic disparities in vaccine and cervical screening uptake on inequality in disease incidence in England.

Methods

We developed an individual-based model of HPV transmission and disease, parameterising it with the latest data for sexual behaviour (from National Survey of Sexual Attitudes and Lifestyles [Natsal-3]) and vaccine and screening uptake by ethnicity (from Publi

SUBMITTER: Johnson HC 

PROVIDER: S-EPMC5765530 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature