Influence of peer review on the reporting of primary outcome(s) and statistical analyses of randomised trials.

ABSTRACT: BACKGROUND:Selective reporting of outcomes in clinical trials is a serious problem. We aimed to investigate the influence of the peer review process within biomedical journals on reporting of primary outcome(s) and statistical analyses within reports of randomised trials. METHODS:Each month, PubMed (May 2014 to April 2015) was searched to identify primary reports of randomised trials published in six high-impact general and 12 high-impact specialty journals. The corresponding author of each trial was invited to complete an online survey asking authors about changes made to their manuscript as part of the peer review process. Our main outcomes were to assess: (1) the nature and extent of changes as part of the peer review process, in relation to reporting of the primary outcome(s) and/or pr

SUBMITTER: Hopewell S 

PROVIDER: S-EPMC5765661 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature