Do pregnancy characteristics contribute to rising childhood cancer incidence rates in the United States?

ABSTRACT:

Background

Since 1975, childhood cancer incidence rates have gradually increased in the United States; however, few studies have conducted analyses across time to unpack this temporal rise. The aim of this study was to test the hypothesis that increasing cancer incidence rates are due to secular trends in pregnancy characteristics that are established risk factors for childhood cancer incidence including older maternal age, higher birthweight, and lower birth order. We also considered temporal trends in sociodemographic characteristics including race/ethnicity and poverty.

Procedure

We conducted a time series county-level ecologic analysis using linked population-based data from Surveillance, Epidemiology, and End Results cancer registries (1975-2013), birth data from the Na

SUBMITTER: Kehm RD 

PROVIDER: S-EPMC5766387 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature