Stilbenoid prenyltransferases define key steps in the diversification of peanut phytoalexins.

ABSTRACT: Defense responses of peanut (Arachis hypogaea) to biotic and abiotic stresses include the synthesis of prenylated stilbenoids. Members of this compound class show several protective activities in human disease studies, and the list of potential therapeutic targets continues to expand. Despite their medical and biological importance, the biosynthetic pathways of prenylated stilbenoids remain to be elucidated, and the genes encoding stilbenoid-specific prenyltransferases have yet to be identified in any plant species. In this study, we combined targeted transcriptomic and metabolomic analyses to discover prenyltransferase genes in elicitor-treated peanut hairy root cultures. Transcripts encoding five enzymes were identified, and two of these were functionally characterized in a transi

SUBMITTER: Yang T 

PROVIDER: S-EPMC5766904 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature