Frequency of the exon 3-deleted/full-length growth hormone receptor polymorphism in Saudi Arabian population.

ABSTRACT:

Objectives

To investigate the frequency of the growth hormone receptor (GHR)-d3 polymorphism in a random sample of Saudi Arabian population from Jazan province, and test the effects of the polymorphism on some anthropometric factors.

Methods

This cross-sectional population-based study was conducted during the period from January to April 2017 at the College of Applied Medical Sciences, Jazan University, Southwestern Saudi Arabia. A total of 230 healthy adult male and female volunteers were randomly recruited. Genomic DNA was extracted from the whole blood, and the GHR exon 3 locus was genotyped using multiplex polymerase chain reaction.

Results

The distributions of the GHR genotypes were as follows: fl/fl (39.1%), fl/d3 (44.8%), and d3/d3 (16.1%). No statistically sig

SUBMITTER: Kaabi YA 

PROVIDER: S-EPMC5767610 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature