Directional local field potentials: A tool to optimize deep brain stimulation.

ABSTRACT:

Background

Although recently introduced directional DBS leads provide control of the stimulation field, programing is time-consuming.

Objectives

Here, we validate local field potentials recorded from directional contacts as a predictor of the most efficient contacts for stimulation in patients with PD.

Methods

Intraoperative local field potentials were recorded from directional contacts in the STN of 12 patients and beta activity compared with the results of the clinical contact review performed after 4 to 7 months.

Results

Normalized beta activity was positively correlated with the contact's clinical efficacy. The two contacts with the highest beta activity included the most efficient stimulation contact in up to 92% and that with the widest therapeutic window

SUBMITTER: Tinkhauser G 

PROVIDER: S-EPMC5768242 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature