Motor Imagery as a Function of Disease Severity in Multiple Sclerosis: An fMRI Study.

ABSTRACT: Motor imagery (MI) is defined as mental execution without any actual movement. While healthy adults usually show temporal equivalence, i.e., isochrony, between the mental simulation of an action and its actual performance, neurological disorders are associated with anisochrony. Unlike in patients with stroke and Parkinson disease, only a few studies have investigated differences of MI ability in multiple sclerosis (MS). However, the relationship among disease severity, anisochrony and brain activation patterns during MI has not been investigated yet. Here, we propose to investigate MI in MS patients using fMRI during a behavioral task executed with dominant/non-dominant hand and to evaluate whether anisochrony is associated with disease severity. Thirty-seven right-handed MS patients, 17 w

SUBMITTER: Tacchino A 

PROVIDER: S-EPMC5768615 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature