Ontology highlight
ABSTRACT:
SUBMITTER: Liu YC
PROVIDER: S-EPMC5768806 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Liu Yu-Chuan YC Tsai Yung-Hsu YH Tang Sung-Chun SC Liou Houng-Chi HC Kang Kai-Hsiang KH Liou Horng-Huei HH Jeng Jiann-Shing JS Fu Wen-Mei WM
Scientific reports 20180115 1
Ischemic stroke is a devastating disease with limited therapeutic options. It is very urgent to find a new target for drug development. Here we found that the blood level of MIF in ischemic stroke patients is upregulated. To figure out the pathological role of MIF in ischemic stroke, both in vitro and in vivo studies were conducted. For in vitro studies, primary cortical neuron cultures and adult rat brain endothelial cells (ARBECs) were subjected to oxygen-glucose deprivation (OGD)/reoxygenatio ...[more]