Identification and Characterization of Sites Where Persistent Atrial Fibrillation Is Terminated by Localized Ablation.

ABSTRACT:

Background

The mechanisms by which persistent atrial fibrillation (AF) terminates via localized ablation are not well understood. To address the hypothesis that sites where localized ablation terminates persistent AF have characteristics identifiable with activation mapping during AF, we systematically examined activation patterns acquired only in cases of unequivocal termination by ablation.

Methods and results

We recruited 57 patients with persistent AF undergoing ablation, in whom localized ablation terminated AF to sinus rhythm or organized tachycardia. For each site, we performed an offline analysis of unprocessed unipolar electrograms collected during AF from multipolar basket catheters using the maximum -dV/dt assignment to construct isochronal activation maps for mul

SUBMITTER: Zaman JAB 

PROVIDER: S-EPMC5769709 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature