A prospective cohort study of body size and risk of head and neck cancers in the NIH-AARP diet and health study.

ABSTRACT:

Background

The association between body size and head and neck cancers (HNCA) is unclear, partly because of the biases in case-control studies.

Methods

In the prospective NIH-AARP cohort study, 218,854 participants (132,288 men and 86,566 women), aged 50 to 71 years, were cancer free at baseline (1995 and 1996), and had valid anthropometric data. Cox proportional hazards regression was used to examine the associations between body size and HNCA, adjusted for current and past smoking habits, alcohol intake, education, race, and fruit and vegetable consumption, and reported as HR and 95% confidence intervals (CI).

Results

Until December 31, 2006, 779 incident HNCAs occurred: 342 in the oral cavity, 120 in the oro- and hypopharynx, 265 in the larynx, 12 in the nasopharyn

SUBMITTER: Etemadi A 

PROVIDER: S-EPMC5772876 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature