Gastrointestinal symptoms in autism spectrum disorder: A review of the literature on ascertainment and prevalence.

ABSTRACT: There is no standard approach to measuring GI symptoms in individuals with ASD, despite postulated interactions. The objectives of this study were to (a) describe the range of GI symptom ascertainment approaches in studies of ASD, (b) describe the range of prevalence estimates across studies, and (c) assess associations between ascertainment approach and prevalence estimates. Studies published from 1/1/1980 to 1/31/2017 were collected via PubMed. Eligibility included studies with at least ten individuals with ASD that measured GI symptoms or conditions. We excluded review and hypothesis papers. We extracted information on study design, GI symptom ascertainment method, demographics, and ASD diagnostic criteria. From a subset of studies, we extracted GI symptom estimates. Out of a possible 3

SUBMITTER: Holingue C 

PROVIDER: S-EPMC5773354 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature