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The Lys469glu/K469E Polymorphism of the Inflammatory Gene Intercellular Adhesion Molecule-1 Lacks any Apparent Role in the Polycystic Ovary Syndrome in Kashmiri Women: A Case Control Study

ABSTRACT: Background: Polycystic ovary syndrome (PCOS), associated with a state of low grade chronic inflammation,

SUBMITTER: Yousuf SD 

PROVIDER: S-EPMC5773772 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature

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The Lys469glu/K469E Polymorphism of the Inflammatory Gene Intercellular Adhesion Molecule-1 Lacks any Apparent Role in the Polycystic Ovary Syndrome in Kashmiri Women: A Case Control Study

Yousuf Syed Douhath SD   Ganie Mohammad Ashraf MA   Zargar Mohammad Afzal MA   Amin Shajr Ul SU   Bhat Gulzar A GA   Masood Akbar A   Rashid Fouzia F  

Asian Pacific journal of cancer prevention : APJCP 20171126 11

Background: Polycystic ovary syndrome (PCOS), associated with a state of low grade chronic inflammation, depends on multiple genetic and environmental factors. Elevated levels of inflammatory markers including intercellular adhesion molecule-1 (ICAM-1) have been demonstrated in affected women. Recent evidence indicates a significant linkage between chromosome 19p13 loci and multifactorial diseases that have an inflammatory component. The aim of this study was to assess the possible association o  ...[more]

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