Index of the human papillomavirus (HPV) vaccine industry clinical study programmes and non-industry funded studies: a necessary basis to address reporting bias in a systematic review.

ABSTRACT:

Background

Unabridged access to drug industry and regulatory trial registers and data reduces reporting bias in systematic reviews and may provide a complete index of a drug's clinical study programme. Currently, there is no public index of the human papillomavirus (HPV) vaccine industry study programmes or a public index of non-industry funded studies.

Methods

By cross-verification via study programme enquiries to the HPV vaccine manufacturers and regulators and searches of trial registers and journal publication databases, we indexed clinical HPV vaccine studies as a basis to address reporting bias in a systematic review of clinical study reports.

Results

We indexed 206 clinical studies: 145 industry and 61 non-industry funded studies. One of the four HPV vaccine ma

SUBMITTER: Jorgensen L 

PROVIDER: S-EPMC5774129 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature