Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study.

ABSTRACT:

Background

Providing supplemental oxygen is fundamental in the management of mechanically ventilated patients. Increasing amounts of data show worse clinical outcomes associated with hyperoxia. However, these previous data in the critically ill have not focused on outcomes associated with brief hyperoxia exposure immediately after endotracheal intubation. Therefore, the objectives of this study were to evaluate the impact of isolated early hyperoxia exposure in the emergency department (ED) on clinical outcomes among mechanically ventilated patients with subsequent normoxia in the intensive care unit (ICU).

Methods

This was an observational cohort study conducted in the ED and ICUs of an academic center in the USA. Mechanically ventilated normoxic (partial pressure of arteri

SUBMITTER: Page D 

PROVIDER: S-EPMC5774130 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature