The benefits and tolerance of exercise in myasthenia gravis (MGEX): study protocol for a randomised controlled trial.

ABSTRACT:

Background

Research exploring the effects of physical exercise in auto-immune myasthenia gravis (MG) is scarce. The few existing studies present methodological shortcomings limiting the conclusions and generalisability of results. It is hypothesised that exercise could have positive physical, psychological as well as immunomodulatory effects and may be a beneficial addition to current pharmacological management of this chronic disease. The aim of this study is to evaluate the benefits on perceived quality of life (QOL) and physical fitness of a home-based physical exercise program compared to usual care, for patients with stabilised, generalised auto-immune MG.

Methods

MGEX is a multi-centre, interventional, randomised, single-blind, two-arm parallel group, controlled trial.

SUBMITTER: Birnbaum S 

PROVIDER: S-EPMC5774148 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature