Individual parcellation of resting fMRI with a group functional connectivity prior.

ABSTRACT: Cortical parcellation based on resting fMRI is an important tool for investigating the functional organization and connectivity of the cerebral cortex. Group parcellation based on co-registration of anatomical images to a common atlas will inevitably result in errors in the locations of the boundaries of functional parcels when they are mapped back from the atlas to the individual. This is because areas of functional specialization vary across individuals in a manner that cannot be fully determined from the sulcal and gyral anatomy that is used for mapping between atlas and individual. We describe a method that avoids this problem by refining an initial group parcellation so that for each subject the parcel boundaries are optimized with respect to that subject's resting fMRI. Initializatio

SUBMITTER: Chong M 

PROVIDER: S-EPMC5774339 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature