When inflammation and depression go together: The longitudinal effects of parent-child relationships.

ABSTRACT: Parent-child relationships have long-term effects on health, particularly later inflammation and depression. We hypothesized that these effects would be mediated by later romantic partner relationships and elevated stressors in young adulthood, helping promote chronic, low grade, inflammation as well as depressive symptoms, and driving their covariation. It has been proposed recently that youth experiencing harsher parenting may also develop a stronger association between inflammation and depressive symptoms in adulthood and altered effects of stressors on outcomes. In the current investigation, we test these ideas using an 18-year longitudinal study of N = 413 African American youth that provides assessment of the parent-child relationship (at age 10), pro-inflammatory cytokine profile an

SUBMITTER: Beach SRH 

PROVIDER: S-EPMC5774864 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature