Molecular genetic studies in Saudi population; identified variants from GWAS and meta-analysis in stroke.

ABSTRACT:

Introduction

Stroke is a multifactorial and heterogeneous disorder, correlates with heritability and considered as one of the major diseases. The prior reports performed the variable models such as genome-wide association studies (GWAS), replication, case-control, cross-sectional and meta-analysis studies and still, we lack diagnostic marker in the global world. There are limited studies were carried out in Saudi population, and we aim to investigate the molecular association of single nucleotide polymorphisms (SNPs) identified through GWAS and meta-analysis studies in stroke patients in the Saudi population.

Methods

In this case-control study, we have opted gender equality of 207 cases and 207 controls from the capital city of Saudi Arabia in King Saud University Hospital.

SUBMITTER: Alharbi KK 

PROVIDER: S-EPMC5775098 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature