Comparative Proteomic Analysis of Hymenolepis diminuta Cysticercoid and Adult Stages.

ABSTRACT: Cestodiases are common parasitic diseases of animals and humans. As cestodes have complex lifecycles, hexacanth larvae, metacestodes (including cysticercoids), and adults produce proteins allowing them to establish invasion and to survive in the hostile environment of the host. Hymenolepis diminuta is the most commonly used model cestode in experimental parasitology. The aims of the present study were to perform a comparative proteomic analysis of two consecutive developmental stages of H. diminuta (cysticercoid and adult) and to distinguish proteins which might be characteristic for each of the stages from those shared by both stages. Somatic proteins of H. diminuta were isolated from 6-week-old cysticercoids and adult tapeworms. Cysticercoids were obtained from exper

SUBMITTER: Sulima A 

PROVIDER: S-EPMC5775281 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature