Applications of random forest feature selection for fine-scale genetic population assignment.

ABSTRACT: Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine-learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with F_ST ranking for selection of single nucleotide polymorphisms (SNP) for fine-scale population assignment. We applied these methods to an unpublished SNP data set for Atlantic salmon (Salmo salar) and a published SNP data set for Alaskan Chinook salmon (Oncorhynchus tshawytscha). In each species, we identified the minimum panel size required to obtain a self-assignment accuracy of at least 90% using each method to create panels of 50-700 mar

SUBMITTER: Sylvester EVA 

PROVIDER: S-EPMC5775496 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature