Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes.

ABSTRACT: BACKGROUND:The severity of the metabolic syndrome (MetS) is significantly associated with future coronary heart disease (CHD) among individuals without baseline Type 2 diabetes. However, the validity of assessing MetS severity among individuals with diabetes is unknown. OBJECTIVE:To assess for differences in MetS severity by timing of Type 2 diabetes diagnosis and to assess for associations between MetS severity and future CHD among individuals with diabetes. METHODS:We analyzed data from participants of the Atherosclerosis Risk in Communities study, including 1419 with- and 7241 without diabetes, followed during 4 visits and adjudicated CHD diagnoses over a 20-year period. We used Cox-regression techniques to assess hazard ratios (HR) of CHD based on a sex- and race/ethnicity-specific Met

SUBMITTER: Gurka MJ 

PROVIDER: S-EPMC5775549 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature