Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites.

ABSTRACT: Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products. Berson and Yalow were the first to develop an immunoassay, known as radioimmunoassay (RIA), for detecting endogenous plasma insulin [1], a development for which Yalow was awarded the Nobel Prize in Physiology or Medicine in 1977. Even today, after half a century, immunoassays are widely utilized with some modifications from the originally proposed system, e.g., radioisotopes have been replaced with enzymes because of safety concerns regarding the use of radioacti

SUBMITTER: Sakamoto S 

PROVIDER: S-EPMC5775980 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature