Detection of synchronous brain activity in white matter tracts at rest and under functional loading.

ABSTRACT: Functional MRI based on blood oxygenation level-dependent (BOLD) contrast is well established as a neuroimaging technique for detecting neural activity in the cortex of the human brain. While detection and characterization of BOLD signals, as well as their electrophysiological and hemodynamic/metabolic origins, have been extensively studied in gray matter (GM), the detection and interpretation of BOLD signals in white matter (WM) remain controversial. We have previously observed that BOLD signals in a resting state reveal structure-specific anisotropic temporal correlations in WM and that external stimuli alter these correlations and permit visualization of task-specific fiber pathways, suggesting variations in WM BOLD signals are related to neural activity. In this study, we provide furth

SUBMITTER: Ding Z 

PROVIDER: S-EPMC5776967 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature