Ontology highlight
ABSTRACT:
SUBMITTER: Aymeric L
PROVIDER: S-EPMC5777054 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20171226 2
Colonization by <i>Streptococcus gallolyticus</i> subsp. <i>gallolyticus</i> (SGG) is strongly associated with the occurrence of colorectal cancer (CRC). However, the factors leading to its successful colonization are unknown, and whether SGG influences the oncogenic process or benefits from the tumor-prone environment to prevail remains an open question. Here, we elucidate crucial steps that explain how CRC favors SGG colonization. By using mice genetically prone to CRC, we show that SGG coloni ...[more]