Candidate biomarkers in the cervical vaginal fluid for the (self-)diagnosis of cervical precancer.

ABSTRACT:

Purpose

Despite improvement in vaccines against human papilloma virus (HPV), the causative agent of cervical cancer, screening women for cervical precancer will remain indispensable in the coming 30-40 years. A simple test that could be performed at home or at a doctor's practice and that informs the woman whether she is at risk would significantly help make a broader group of patients who aware that they need medical treatment. Cervical vaginal fluid (CVF) is a body fluid that is very well suited for such a test.

Methods

Narrative review of cervical (pre)cancer candidate biomarkers from cervicovaginal fluid, is based on a detailed review of the literature. We will also discuss the possibilities that these biomarkers create for the development of a self-test or point-of-care

SUBMITTER: Van Ostade X 

PROVIDER: S-EPMC5778162 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature