Associations of social environment, socioeconomic position and social mobility with immune response in young adults: the Jerusalem Perinatal Family Follow-Up Study.

ABSTRACT: OBJECTIVES:Immune response to cytomegalovirus (CMV) impacts adult chronic disease. This study investigates associations of childhood and adulthood social environment, socioeconomic position (SEP) and social mobility with CMV response in young adults. DESIGN:Historical prospective study design. SETTING:Subcohort of all 17 003 births to residents of Jerusalem between 1974 and 1976. PARTICIPANTS:Participants included 1319 young adults born in Jerusalem with extensive archival and follow-up data, including childhood and adulthood SEP-related factors and anti-CMV IgG titre levels and seroprevalence measured at age 32. MAIN EXPOSURE AND OUTCOME MEASURES:Principal component analysis was used to transform correlated social environment and SEP-related variables at two time points (childhood and adu

SUBMITTER: Lawrence GM 

PROVIDER: S-EPMC5778288 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature