Association between total dose of ritodrine hydrochloride and pulmonary oedema in twin pregnancy: a retrospective cohort study in Japan.

ABSTRACT: OBJECTIVE:Pulmonary oedema is recognised as a severe side effect of ritodrine hydrochloride. Recently, the number of twin pregnancies has been increasing. Few studies have reported the association between total dose of ritodrine hydrochloride prior to delivery and pulmonary oedema in twin pregnancy. We aimed to examine this association and determine the optimal cut-off threshold of total ritodrine hydrochloride dose to predict the incidence of pulmonary oedema in twin pregnancy based on obstetric records. DESIGN:Retrospective cohort study. SETTING:Yamanashi Prefectural Central Hospital, Japan. PARTICIPANTS:Two hundred and twenty-six women with twin pregnancy who delivered at Yamanashi Prefectural Central Hospital between September 2009 and November 2016. METHODS:The obstetric records of th

SUBMITTER: Shinohara S 

PROVIDER: S-EPMC5778295 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature