Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil.

ABSTRACT:

Background

Zika virus (ZIKV) has been identified in several body fluids of infected individuals. In most cases, it remained detected in blood from few days to 1 week after the onset of symptoms, and can persist longer in urine and in semen. ZIKV infection can have dramatic consequences such as microcephaly and Guillain-Barré syndrome. ZIKV sexual transmission has been documented. A better understanding of ZIKV presence and persistence across biologic compartments is needed to devise rational measures to prevent its transmission.

Methods

This observational cohort study will recruit non-pregnant participants aged 18 years and above with confirmed ZIKV infection [positive reverse transcriptase-polymerase chain reaction (RT-PCR) test in blood and/or urine]: symptomatic men and w

SUBMITTER: Calvet GA 

PROVIDER: S-EPMC5778641 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature