Personalized medicine in colorectal cancer diagnosis and treatment: a systematic review of health economic evaluations.

ABSTRACT:

Background

Due to its epidemiological relevance, several studies have been performed to assess the cost-effectiveness of diagnostic tests and treatments in colorectal cancer (CRC) patients.

Objective

We reviewed economic evaluations on diagnosis of inherited CRC-syndromes and genetic tests for the detection of mutations associated with response to therapeutics.

Methods

A systematic literature review was performed by searching the main literature databases for relevant papers on the field, published in the last 5 years.

Results

20 studies were included in the final analysis: 14 investigating the cost-effectiveness of hereditary-CRC screening; 5 evaluating the cost-effectiveness of KRAS mutation assessment before treatment; and 1 study analysing the cost-effectiv

SUBMITTER: Guglielmo A 

PROVIDER: S-EPMC5778687 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature