Can computerized cognitive training reverse the diagnosis of HIV-associated neurocognitive disorder? A research protocol.

ABSTRACT: Nearly 50% of adults with HIV have some form of HIV-associated neurocognitive disorder (HAND), ranging from subtle to symptoms that interfere with everyday functioning and quality of life. HAND is diagnosed when a person performs more than 1 standard deviation below his or her normative mean on standardized measures in two or more cognitive domains (e.g., attention, speed of processing, verbal memory, executive functioning). As adults age with HIV, they are more likely to develop comorbidities such as cardiovascular disease, hypertension, and insulin resistance that may further contribute to poorer cognitive functioning and HAND. Certain computerized cognitive training programs may be able to improve specific cognitive domains in those with HIV. Such programs may be effective in changing t

SUBMITTER: Vance DE 

PROVIDER: S-EPMC5780199 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature