BRCA mutations in women with inflammatory breast cancer.

ABSTRACT:

Background

Inflammatory breast cancer (IBC) often affects women at a relatively young age. To the authors' knowledge, the rate of BRCA variants among patients with IBC is not known. To determine the association between BRCA status and IBC, the authors evaluated its rate and compared the clinicopathologic characteristics of patients with IBC with those of patients with other breast cancers (non-IBC).

Methods

Patients who presented at the study institution's cancer genetics program and who underwent BRCA genetic testing were included in the current study. The authors compared clinicopathologic data between patients with IBC and those with non-IBC using propensity score matching to identify predictors.

Results

A total of 1789 patients who underwent BRCA genetic testing (

SUBMITTER: Gutierrez Barrera AM 

PROVIDER: S-EPMC5780239 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature