PGAP-X: extension on pan-genome analysis pipeline.

ABSTRACT:

Background

Since PGAP (pan-genome analysis pipeline) was published in 2012, it has been widely employed in bacterial genomics research. Though PGAP has integrated several modules for pan-genomics analysis, how to properly and effectively interpret and visualize the results data is still a challenge.

Result

To well present bacterial genomic characteristics, a novel cross-platform software was developed, named PGAP-X. Four kinds of data analysis modules were developed and integrated: whole genome sequences alignment, orthologous genes clustering, pan-genome profile analysis, and genetic variants analysis. The results from these analyses can be directly visualized in PGAP-X. The modules for data visualization in PGAP-X include: comparison of genome structure, gene distribution

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC5780747 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature