Analytical detection of influenza A(H3N2)v and other A variant viruses from the USA by rapid influenza diagnostic tests.

ABSTRACT:

Background

The performance of rapid influenza diagnostic tests (RIDTs) that detect influenza viral nucleoprotein (NP) antigen has been reported to be variable. Recent human infections with variant influenza A viruses that are circulating in pigs prompted the investigation of the analytical reactivity of RIDTs with these variant viruses.

Objectives

To determine analytical reactivity of seven FDA-cleared RIDTs with influenza A variant viruses in comparison with the reactivity with recently circulating seasonal influenza A viruses.

Methods

Tenfold serial dilutions of cell culture-grown seasonal and variant influenza A viruses were prepared and tested in duplicate with seven RIDTs.

Results

All RIDTs evaluated in this study detected the seasonal influenza A(H3N2) vi

SUBMITTER: Balish A 

PROVIDER: S-EPMC5780998 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature