Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study.

ABSTRACT:

Background

In the critically ill, energy delivery from enteral nutrition (EN) is often less than the estimated energy requirement. Parenteral nutrition (PN) as a supplement to EN may increase energy delivery. We aimed to determine if an individually titrated supplemental PN strategy commenced 48-72 hours following ICU admission and continued for up to 7 days would increase energy delivery to critically ill adults compared to usual care EN delivery.

Methods

This study was a prospective, parallel group, phase II pilot trial conducted in six intensive care units in Australia and New Zealand. Mechanically ventilated adults with at least one organ failure and EN delivery below 80% of estimated energy requirement in the previous 24 hours received either a supplemental PN strategy

SUBMITTER: Ridley EJ 

PROVIDER: S-EPMC5781264 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature