Genetical genomics of growth in a chicken model.

ABSTRACT:

Background

The genetics underlying body mass and growth are key to understanding a wide range of topics in biology, both evolutionary and developmental. Body mass and growth traits are affected by many genetic variants of small effect. This complicates genetic mapping of growth and body mass. Experimental intercrosses between individuals from divergent populations allows us to map naturally occurring genetic variants for selected traits, such as body mass by linkage mapping. By simultaneously measuring traits and intermediary molecular phenotypes, such as gene expression, one can use integrative genomics to search for potential causative genes.

Results

In this study, we use linkage mapping approach to map growth traits (N = 471) and liver gene expression (N = 130) in an adva

SUBMITTER: Johnsson M 

PROVIDER: S-EPMC5782384 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature