P07.14 Correlation of molecular and imaging biomarkers in primary brain tumours

ABSTRACT: Abstract

Purpose:

Positron emission tomography with carbon-11 labelled methionine (11C-METH PET) is a well-established imaging modality allowing to characterise tumour lesions on a metabolic and molecular level. The aim of the current study was to evaluate the relationship between 11C-METH PET semi-quantitative metrics and molecular biomarkers in patients affected by brain gliomas candidate to surgery, and determine their prognostic role with respect to disease outcome.

Materials and Methods:

A consecutive series of 145 patients affected by pathologically proven gliomas, who were referred to our Institution for tumour resection from March 2012 to January 2015 and submitted to pre-operative evaluation with 11C-METH PET, was retrospectively analyzed. The trial was registere

SUBMITTER: Lopci E 

PROVIDER: S-EPMC5782621 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature