Adenovirus Type 4 Respiratory Infections among Civilian Adults, Northeastern United States, 2011-20151.

ABSTRACT: Human adenovirus type 4 (HAdV-4) is most commonly isolated in military settings. We conducted detailed molecular characterization on 36 HAdV-4 isolates recovered from civilian adults with acute respiratory disease (ARD) in the northeastern United States during 2011-2015. Specimens came from college students, residents of long-term care facilities or nursing homes, a cancer patient, and young adults without co-morbidities. HAdV-4 genome types 4a1 and 4a2, the variants most frequently detected among US military recruits in basic training before the restoration of vaccination protocols, were isolated in most cases. Two novel a-like variants were recovered from students enrolled at a college in Tompkins County, New York, USA, and a prototype-like variant distinguishable from the vaccine strain

SUBMITTER: Kajon AE 

PROVIDER: S-EPMC5782899 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature