The meaning of the blood urea nitrogen/creatinine ratio in acute kidney injury.

ABSTRACT:

Background

A blood urea nitrogen (BUN)/creatinine ratio (BCR) >20 (0.081 in international unit) is used to distinguish pre-renal azotemia (PRA) and acute tubular necrosis (ATN). However, there is little evidence that BCR can distinguish between these two conditions and/or is clinically useful.

Methods

We conducted a retrospective study using a large hospital database. Patients were divided into three groups: 'low BCR' (if BCR when acute kidney injury (AKI) developed was ≤20), 'high BCR' (if BCR when AKI developed was >20) and 'no AKI' if patients did not satisfy any of the Risk, Injury, Failure, Loss and End-stage kidney disease criteria for AKI during hospitalization.

Results

Among 20 126 study patients, 3641 (18.1%) had AKI. Among these patients, 1704 (46.8%) had a

SUBMITTER: Uchino S 

PROVIDER: S-EPMC5783213 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature