Has Toxicity Testing Moved into the 21st Century? A Survey and Analysis of Perceptions in the Field of Toxicology.

ABSTRACT:

Background

Ten years ago, leaders in the field of toxicology called for a transformation of the discipline and a shift from primarily relying on traditional animal testing to incorporating advances in biotechnology and predictive methodologies into alternative testing strategies (ATS). Governmental agencies and academic and industry partners initiated programs to support such a transformation, but a decade later, the outcomes of these efforts are not well understood.

Objectives

We aimed to assess the use of ATS and the perceived barriers and drivers to their adoption by toxicologists and by others working in, or closely linked with, the field of toxicology.

Methods

We surveyed 1,381 toxicologists and experts in associated fields regarding the viability and use of ATS

SUBMITTER: Zaunbrecher V 

PROVIDER: S-EPMC5783667 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature