Links between inflammation, amygdala reactivity, and social support in breast cancer survivors.

ABSTRACT: Psychosocial stress can affect inflammatory processes that have important consequences for cancer outcomes and the behavioral side effects of cancer treatment. To date, however, little is known about the upstream neural processes that may link psychosocial stressors and inflammation in cancer patients and survivors. To address this issue, 15 women who had been diagnosed with early-stage breast cancer and completed cancer treatment and 15 age- and ethnicity-matched women with no cancer history were recruited for a neuroimaging study. Participants provided a blood sample for levels of circulating inflammatory markers (CRP and IL-6), underwent an fMRI scan in which they completed a threat reactivity task designed to elicit activity in the amygdala, and reported their levels of perceived socia

SUBMITTER: Muscatell KA 

PROVIDER: S-EPMC5784760 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature